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Fantasy Forecaster updated Sunday, Sept. 4, at 10:19 p.m. ET.On tap: A pair of aces should rejoin their respective division-leading teams during Week 22: Clayton Kershaw of the Los Angeles Dodgers and Stephen Strasburg of the Washington Nationals. Kershaw is on track for a Sept. 9 return, setting up an electric pitchers duel versus?Miami Marlins ace Jose Fernandez at Marlins Park. Strasburg, meanwhile, is a candidate to return on Sept. 7.The Boston Red Soxs Drew Pomeranz returns to San Diegos Petco Park to face his former team, the San Diego Padres, on Sept. 5. Pomeranz, incidentally, has four wins, five quality starts, a 2.64 ERA and a 1.11 WHIP in eight starts at Petco this year.Just days after rumors swirled that the Los Angeles Dodgers were considering making a run at reacquiring Zack Greinke, now the Arizona Diamondbacks ace, Greinke heads to Dodger Stadium to face his former mates on Sept. 5. Itll be his first start there since he signed his six-year, $206.5 million deal with the Diamondbacks in December 2015, and keep in mind that among pitchers with at least 15 career starts there, Greinkes career 2.00 ERA and 0.93 WHIP at Dodger Stadium are second-best in history behind only Sandy Koufax (1.37 and 0.82).The wild-card races have some key series matchups during Week 22. The Baltimore Orioles visit the Detroit Tigers?from Sept. 9-11;?these teams are tied for the American Leagues second wild-card spot entering play on Sept. 5. Meanwhile, the St. Louis Cardinals visit the Pittsburgh Pirates?from Sept. 5-7; the Cardinals?lead by the Pirates by 3.5 games for the National Leagues second wild-card spot.Among the weeks schedule oddities: All 30 teams play on Labor Day (Monday), and a whopping 21 teams will play in a different city Sunday. Of those 21, 11 play day games that begin no later than 24 hours after the start times of their Sept. 4 contests. Its a potentially tiring travel schedule that explains why 16 teams have Thursday off. Unsurprisingly, seven of those aforementioned 11 teams that play in 24 hours or less on Sunday-Monday are off Thursday.The Nationals and New York Mets have it especially rough, playing the Sunday Night Baseball game, with the Nationals then returning home for a game roughly 20 hours later and playing all seven days in Week 22, while the Mets hit the road to battle the Cincinnati Reds roughly 17 hours later. The Mets, unlike the Nationals, do have Thursday off.Quickly jump to any section, if you want specific intelESPN lineup deadlinesInterleague impactProjected starting pitchersPitching scuttlebuttWeek 22 pitcher rankingsHitting ratingsHitting advantagesESPN leagues: Lineup deadlinesThe Labor Day holiday causes an early start to Week 22, as the first game starts at 1 p.m. ET: Chicago Cubs at Milwaukee Brewers on ESPN/WatchESPN. Its the first game of an ESPN doubleheader; Cardinals at Pirates begins at 4 p.m. ET. Make sure to set your lineups early before heading out for your holiday activities.Remember that game times have tremendous influence upon daily planning, so be aware of every days first scheduled pitch. This week, they are:Monday, Sept. 5 -- 1 p.m. ET (Cubs at Brewers, one of 13 day games) Tuesday, Sept. 6 -- 7 p.m. ET (Houston Astros at Cleveland Indians) Wednesday, Sept. 7 -- 12:35 p.m. ET (New York Mets at Cincinnati Reds, one of four day games) Thursday, Sept. 8 -- 12:10 p.m. ET (Astros at Indians, the days only day game) Friday, Sept. 9 -- 7:05 p.m. ET (three games begin at that time) Saturday, Sept. 10 -- 1:05 p.m. ET (Cubs at Astros, one of four day games) Sunday, Sept. 11 -- 1:05 p.m. ET (Tampa Bay Rays at New York Yankees, one of 14 day games)Interleague impactThis weeks interleague series:Boston Red Sox at San Diego Padres (3 games, Sept. 5-7)Chicago Cubs at Houston Astros (3 games, Sept. 9-11)Red Soxs traditional DH, 3 games in NL ballparks: David Ortiz, who will be making the final trip of his career to a National League ballpark. He has made only one start at first base this season, on Aug. 6 at Los Angeles, out of five interleague games at NL parks that were against a right-handed starter, and manager John Farrell said on Sept. 4 that Ortiz will not start there in San Diego and instead will serve as a pinch hitter. The lost at-bats could make Ortiz someone to sit in ESPN standard leagues, but three starts plus pinch-hitting at-bats is enough to make him relevant in any deeper format.Cubs probable DH(s), 3 games in AL ballparks: Jorge Soler served as the DH in all three games at Oakland Aug. 5-7, freeing up catcher/second base/third base/corner outfielder at-bats for other players on this Cubs roster that has a lot of flexibility. Thanks to his .302/.366/.603 triple-slash rates in 22 games since his return from the DL, Soler will likely do the same in all three games at Houston, granting the mix of Javier Baez, Miguel Montero and Chris Coghlan the greatest odds of picking up an additional start (or thre